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Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons
Title / Series / Name
Publication Volume
Publication Issue
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Keywords
Statistics and Probability
Information Systems
Education
Computer Science Applications
Statistics, Probability and Uncertainty
Library and Information Sciences
Information Systems
Education
Computer Science Applications
Statistics, Probability and Uncertainty
Library and Information Sciences
URI
https://hdl.handle.net/20.500.14018/27166
Abstract
Lesioning studies have provided important insight into the functions of brain regions in humans and other animals. In the nematode Caenorhabditis elegans, with a small nervous system of 302 identified neurons, it is possible to generate lesions with single cell resolution and infer the roles of individual neurons in behaviour. Here we present a dataset of ∼300 video recordings representing the locomotor behaviour of animals carrying single-cell ablations of 5 different motorneurons. Each file includes a raw video of approximately 27,000 frames; each frame has also been segmented to yield the position, contour, and body curvature of the tracked animal. These recordings can be further analysed using publicly-available software to extract features relevant to behavioural phenotypes. This dataset therefore represents a useful resource for probing the neural basis of behaviour in C. elegans, a resource we hope to augment in the future with ablation recordings for additional neurons.
Topic
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Place of Publication
Type
Journal article
Date
2017-10-19
Language
ISBN
Identifiers
10.1038/sdata.2017.156